Mad Cow Disease is Not a Large Cause for Fear :: CJD MCD BSE Prion Diseases Bovine Spongiform

Mad appal affection A Cause for Fear?Abstract Mad Cow ailment, a disorder well shaftn and well feared, is not as deathlike as most muckle believe it to be. In fact, most people live on little of this illness and what little they knowusually call on out to be false facts. MCD is a prion-based disease where an infected protein converts level-headed proteins into the infectious state. There is no cure and the disease is fatal and to this year, therehave been little over 150 cases of the human indication of the disease, variant Creutzfeldt - Jakob disease,world-wide. Thus, MCD does not deserve the fear and attention that it commands.Although the name, Mad Cow Disease is instantly recognizable by everyone today, few peopleknow it for what it actually is. However, no matter how little they know about this disease, everybodyacknowledges the venomous capabilities it possesses. Personally, I find it interesting and feel it onlynatural that, as humans, we fear what we do not entirel y understand simply be sustain we know what willhappen. It is only natural that we feel threatened at the beginning(a) sign of danger. Thus, it is important toin take shape others about Mad Cow Disease so that they will at least know what they fear.Bovine Spongiform Encephalopathy, normally known as Mad Cow Disease, first appeared around1985 in Great Britain as a result of the special animal viands that consisted of ground up sheep fed to thecattle. Between the years 1992 and 1995, a study bovine spongiform encephalitis outbreak occurred in Great Britain, which causedthe countrys beef industry to suffer. Since 2003, the unite States have only had three reportedincidents of mad cow disease in humans8.A prion is a disease-carrying agent that is composed entirely of proteins. It is the cause ofnumerous diseases in mammals, all of which target the brain specifically. Also neb that all prion-baseddisorders are fatal and that there are currently no known cures for any of them. All kn own prionsinduce the formation of an starchy fold, in which the protein polymerizes into an aggregate consistingof tightly packed beta sheets3 thus, converting into its infectious state.BSE is a prion-based disease where the infectious protein causes other prion proteins in the brain tomisfold and variety into the infectious state. Thisprocess continues until it forms proteinaggregates, which are large clumps of mis-foldedproteins which in turn form plaque, giving theappearance of holes in the brain. Cows withthis disease show signs including changes inmental state and abnormalities in posture,movement and sensation4.