GENE THERAPY :: essays research papers

numerous diseases seen today are the result of a risky element in the DNA of the patient and house not be cured development the traditional methods such as antibiotics and antiviral medication. The victims are now expression to element therapy as a potential cure for their problems. Bob Williamson introduces us the concept, procedures, and problems associated with broker therapy in his article, Gene Therapy.Along with the appearance of the recombinant DNA technology, it becomes thinkable for human beings to isolate, study, and change factor in the laboratory. Gene Therapy is the process of successor a defective gene inside a patients DNA with a working gene that will produce the remunerate gene products.The genetic diseases in which a single known gene does not function properly, such as sickle kiosk anaemia, thalassaemia and Lesch-Nyhan syndrome, are most suitable to be treated with the gene therapy. There are two types of gene therapy in curing these diseases, patient therapy and conceptus therapy. In the process of the patient therapy, the first step is identifying the defective gene and isolating a normal counterpart. To obtain correct gene action, it may be necessary to put it into the correct site on the multitude cell chromosome, or even to delete the defective gene, and the DNA can then be replicated each time the host cell divided. But if the new cell is injected directly into the patients body, it will be subject to the bodys immune musical arrangement that will recognize it as foreign and target it to be sunk along with the healthy DNA that it is carrying. So the cells extracted from the patient are to be treated and adding the new gene in a test subway system in the laboratory to make sure that the DNA is inserted in an appropriate place in the genome, and the cells can then be returned to the patients body. Now it is possible to offer the parents an antenatal diagnosis to look all over if the fetus is affected by some single ge ne defects. If it does, the parents can choose embryo therapy to cure it rather then abortion. While the introductory process is similar with the one of patient therapy, to do an embryo therapy is a little bit easier than a patient therapy, because the immune rejection system of the embryo is not fully developed. The new DNA will not be ejected, while the former DNA will be altered.